Molecular Details
DICL_CP_0307575
- barium
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0307575
PubChem CID
Molecular Formula
Ba Molecular Weight
137.328 g/mol
Synonyms/Alias
[7440-39-3; Ba; Barium; bario; baryum; Barium; elemental; Barium metal; Bario; Baryum; 24GP945V5T; MFCD00134031; HSDB 4481; Barium Standard: Ba+2 @ 1000 microg/mL in H2O; EINECS 231-149-1; UN1400; Bar...
InChI Key
DSAJWYNOEDNPEQ-UHFFFAOYSA-N
InChI
InChI=1S/Ba
IUPAC Name
barium
CAS Number
7727-43-7
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
1 0 0 0 0 0 0 0 0 0999 V2000
0.0000 0.0000 0.0000 Ba 0 0 0 0 0 15 0 0 0 0 0 0
M END
$$$$
Experimental Data
Activity Data
Target Ion Channel
G protein activated inward rectifier potassium channel 4
Uniprot Accession Number
Function
Blocker
Species
Homo sapiens (Human)
IC50
N/A (Not available)
EC50
EC50: 730 nM
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
−100 to 100 mV mV
Temperature
Not mention
Test Method
Patch-clamping
Test Species
Not specified
Binding Information
Binding Site
Transmembrane domain
Binding Site Residue
D172 and I176 within M2 segment of Inward rectifier potassium channel 2
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
1
Rotatable Bonds
0
logP
-0.3808
Complexity
5.754
TPSA (Ų)
0
H-Bond Donors
0
H-Bond Acceptors
0
Ring Count
0